T Cells FOXP 3 Target Genes in Natural Regulatory

Neuropilin-1highCD4+CD25+ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

Regulatory T cells (Tregs) appear to be involved in sepsis-induced immune dysfunction; neuropilin-1 (Nrp-1) was identified as a surface marker for CD4(+)CD25(+)Tregs. In the current study, we investigated the negative immunoregulation of Nrp-1(high)CD4(+)CD25(+)Tregs and the potential therapeutic value of Nrp-1 in sepsis. Splenic CD4(+)CD25(+)Tregs from cecal ligation and puncture (CLP) mouse m...

[Frontiers in Bioscience 11, 1607-1619, May 1, 2006] 1607 Insights into transcriptional regulation by FOXP3

1. Abstract 2. The Fox family of transcription factors 3. Fox Family Members in the Immune System 3.1. FoxD1/2 3.2. FoxN1 3.3. FoxJ1 3.4. FoxO 4. Discovery of the FoxP subfamily 5. Role of FOXP subfamily members in human disease 6. FoxP3: the black sheep of the FoxP subfamily 6.1 Identification of FoxP3 6.2. FoxP3 function 6.3. Role of transcriptional co-repressors in FoxP function 6.4. Structu...

Regulatory CD 4 + FOXP 3 + Helicobacter pylori - induced disease T cells in Bert

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T Regulatory Cell Responses to Immunization with a Soluble Egg Antigen in Schistosoma mansoni-Infected Mice

The aim of the study is to characterize the phenotypes of CD4(+) CD25(+) T regulatory cells within the liver granulomas and association with both Foxp-3 gene expression and splenic cytokines. Naïve C57BL/6 mice were intravenously injected with multiple doses of the soluble egg antigen (SEA) 7 days before cercarial infection. The immunized and infected control groups were sacrificed 8 and 16 wee...

Revert into Conventional Effector CD 4 Foxp 3 - Deficient Regulatory T Cells Do Not